Molecular Details
DICL_CP_0307086
- chloronickel
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0307086
PubChem CID
Molecular Formula
ClNi Molecular Weight
94.146 g/mol
Synonyms/Alias
[Chloronickel; 13931-83-4; Chlornickel; Nickel monochloride; Nickel chloride (NiCl); DTXSID20904915]
InChI Key
GGVOVPORYPQPCE-UHFFFAOYSA-M
InChI
InChI=1S/ClH.Ni/h1H;/q;+1/p-1
IUPAC Name
chloronickel
CAS Number
7718-54-9
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
2 1 0 0 0 0 0 0 0 0999 V2000
-0.7500 0.0000 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0
0.7500 -0.0000 0.0000 Ni 0 0 0 0 0 1 0 0 0 0 0 0
1 2 1 0
M...
Experimental Data
Activity Data
Target Ion Channel
Two-pore domain potassium channel subfamily K member 18
Uniprot Accession Number
Function
Inhibitor
Species
Homo sapiens (Human)
IC50
IC50: >100000 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
pH 7.3
Holding Potential
−120 to 60 mV mV
Temperature
25 °C
Test Method
Patch-clamping
Test Species
HEK293 cell (Homo sapiens embryonic kidney 293 cell)
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
2
Rotatable Bonds
0
logP
0.687
Complexity
5.853
TPSA (Ų)
0
H-Bond Donors
0
H-Bond Acceptors
0
Ring Count
0